PKD (ADPKD) is the most common form of PKD. It accounts for about 90% of
all PKD cases. Autosomal dominant means that if one parent has the
disease there is a 50% chance that the disease will pass to a child. Both
males and females are equally affected.
ADPKD used to be
called adult polycystic kidney disease. It is often diagnosed in
adulthood. Usually, at least one parent must have the disease for a child
to inherit it. In 10% of cases, there may be no family history of PKD.
These cases are new mutations in a family. In very few cases, this type
of PKD happens suddenly after conception. Parents would not be at
increased risk to have more children with PKD. But people with PKD have a
50/50 chance of passing the gene on to their children.
Symptoms often start
between age 30 and 40. But they can begin in childhood. They may
Pale color to
(bulging of the walls of blood vessels) in the brain
(pouches in the intestines)
(blood in the urine)
ADPKD may happen
with other conditions, such as:
sclerosis (a genetic syndrome involving seizures, intellectual
disability, benign tumors, and skin lesions)
of ADPKD sometimes look like other health problems. Always see your
healthcare provider for a diagnosis.
Diagnosis of ADPKD
may include the use of imaging tests to detect cysts on the kidney and
other organs and a review of the family history. There are 3 different
dominant genes that have been identified. They further subdivide this
type into PKD1, PKD2, and PKD3.
provider will create a treatment plan after careful consideration of
symptoms and medical history. Treatment may include:
shrink cysts and ease pain
high blood pressure
urinary tract infections