GLA is said to be relatively safe. However, there are concerns that borage oil may be toxic. Evening primrose oil seems to be a safer source of GLA than borage oil.
Both borage oil and evening primrose oil may lower the seizure threshold. People who take anticonvulsant medicines should not take these oils. Some omega-6 fatty acids, such as GLA, may increase or decrease the effects of certain medicines. Talk to your healthcare provider before taking borage oil.