Fibrous dysplasia is a chronic problem in which scar-like tissue grows in place of normal bone. It often results in one or more, of the following:
Any bone can be affected. More than one bone can be affected at any one time. When multiple bones are affected, it is not unusual for them to all be on one side of the body. However, fibrous dysplasia does not spread from one bone to another. The most commonly affected bones include the following:
Some people develop hormonal problems and a condition called McCune-Albright syndrome. McCune-Albright syndrome is another form of fibrous dysplasia. It causes different symptoms, such as early onset of puberty and skin spots, called café-au-lait spots.
Fibrous dysplasia usually occurs in children ages 3 to 15. It is sometimes not diagnosed until adulthood. It is found equally in men and women.
The exact cause of fibrous dysplasia is not known. It is believed to be due to a chemical defect in a specific bone protein. This defect may be due to a gene mutation present at birth, although the condition is not known to be passed down in families.
The following are the most common symptoms for fibrous dysplasia. However, each person may experience symptoms differently. Symptoms may include:
The symptoms of fibrous dysplasia may look like other medical problems. Always talk with your healthcare provider for a diagnosis.
In addition to a complete medical history and physical exam, other tests may include:
Specific treatment for fibrous dysplasia will be determined by your healthcare provider based on:
Surgical treatment may include the following procedures:
Other treatment may include:
Fibrous dysplasia is a chronic disorder in which scar-like tissue grows in place of normal bone. Any bone can be affected.
Tips to help you get the most from a visit to your healthcare provider:
The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637 | 773-702-1000
Appointments: Call UCM Connect at 1-888-824-0200